News Health & Medicine The first CRISPR therapy approved in the U.S. will treat sickle cell disease The gene-editing treatment aims to help people with recurring pain crises People with sickle cell disease have inflexible, curved blood cells (shown in this SEM image) that get stuck in blood vessels and block blood flow to tissues, causing bouts of debilitating pain. Callista Images/Getty Images Share this:EmailFacebookTwitterPinterestPocketRedditPrint By Erin Garcia de Jesús December 8, 2023 at 12:46 pm U.S. patients with sickle cell disease now have a novel treatment option: the first-ever CRISPR-based therapy.